About Cold-EEZE^®:
Using Zinc Gluconate For Colds

Cold-EEZE reduces the duration of the common cold by nearly half.

It actually shortens your cold to help you get well sooner! 

Here are a few things you should know:

• Cold-EEZE treatment should begin as soon as possible when the very first symptoms of a cold start to appear, such as scratchy or sore throat, coughing, stuffiness, etc.
• The Cold-EEZE brand is the #1 pharmacist-recommended zinc cold remedy. (Source: Pharmacy Times OTC survey – June 2011, page 18)
• Cold-EEZE uses natural flavors and has no preservatives or colors. It is non-drowsy, non-agitating and does not affect blood pressure.
• Cold-EEZE has millions of fans!

Although the precise mechanism by which zinc ions interfere with the cold virus has not been scientifically established, the Cleveland Clinic Study demonstrated that Cold-EEZE lozenges significantly reduced the duration of the common cold.

Prasad AS, Beck FWJ, Bao B, Snell D, Fitzgerald JT. Duration and severity of symptoms and level of plasma Interleukin-1 receptor antagonist, soluble tumor necrosis factor receptor, and adhesion molecules in patients with common cold treated with zinc acetate. Journal of Infectious Diseases 2008; 197:795-802.

Novick SG, Godfrey JC, Godfrey NJ, Wilder HR. How does zinc modify the common cold? Clinical observations and implications regarding mechanisms of action. Medical Hypotheses 1996; 46:295–302.

For Best Results:

• Cold-EEZE treatment should begin within 24-48 hours of the start of a cold and be used daily until all symptoms resolve. The earlier, the better.
• Completely dissolve a Cold-EEZE lozenge in your mouth. Do not chew. Repeat every 2 to 4 hours as needed.
• The recommended daily dosage is 6 lozenges per day, which means an 18 count bag/box is a 3-day supply of Cold-EEZE for adults.
• Children 12-17 can take 4 lozenges per day.
• Consult your healthcare professional before giving Cold-EEZE to children under 12 years of age.
• Cold-EEZE is safe to take with most other medications including other symptom relievers.
• Avoid stomach upset — do not take Cold-EEZE lozenges on an empty stomach.
• Avoid citrus fruits and juices, as well as other products containing citric acid, 30 minutes before and after taking Cold-EEZE lozenges, as they may diminish product effectiveness.
• Zinc may interfere with the absorption of minocycline, doxycycline, tetracycline as well as Coumadin. If you’re taking one of these medicines, consult with your physician prior to using Cold-EEZE.
• Clinical studies demonstrated that results will vary but that on average, Cold-EEZE will shorten your cold by nearly half. As a consumer, if you are not satisfied with the results from taking Cold-EEZE, please contact us to receive a full refund of your purchase price.

Learn more about the clinical research behind Cold-EEZE and how it shortens your cold to help you get well sooner!

Get well sooner ... with Cold‐EEZE®

You don't have to take our word for it! Cold-EEZE has peer reviewed and published clinical studies that show the powerful and safe effects of its proprietary formula.

	An Open-Label Single-Center, Phase IV Clinical Study of the Effectiveness of Zinc Gluconate Glycine Lozenges (Cold-Eeze) in Reducing the Duration and Symptoms of the Common Cold in School-Aged Subjects
	Zinc Gluconate and the Common Cold: a Controlled Clinical Study
	Zinc Gluconate Lozenges for Treating the Common Cold
	Effectiveness of Zinc Gluconate Glycine Lozenges (Cold-Eeze) Against the Common Cold in School-Aged Subjects: A Retrospective Chart Review

List of relevant scientific studies related to zinc and common colds:

Geist 1987
Geist F, Bateman J, Hayden F. In vitro activity of zinc salts against human rhinoviruses.

Antimicrobial Agents and Chemotherapy 1987;31:622–4.

Novick 1996
Novick SG, Godfrey JC, Godfrey NJ, Wilder HR. How does zinc modify the common cold? Clinical observations and implications regarding mechanisms of action.

Medical Hypotheses 1996;46:295–302.

Korant 1976
Korant BD, Butterworth BE. Inhibition by zinc of rhinovirus protein cleavage: interaction of zinc with capsid polypeptides.

Journal of Virology 1976;18:298–306.

Prasa 2008
Prasad AS, Beck FWJ, Bao B, Snell D, Fitzgerald JT. Duration and severity of symptoms and level of plasma Interleukin-1 receptor antagonist, soluble tumor necrosis factor receptor, and adhesion molecules in patients with common cold treated with zinc acetate.

J Infect Dis 2008; 197:795-802.

Eby 2004
Eby GA. Zinc lozenges: cold cure or candy? Solution chemistry determinations.

Bioscience Reports 2004;24:23–39.

Singh 2011
Singh M, Das RR. Zinc for the common cold. Cochrane Database of

Systematic Reviews 2011, Issue 2. Art. No.: CD001364.
DOI: 10.1002/14651858.CD001364.pub3.

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Two Sprays & Go!

Two Sprays & Go!

The new Cold-EEZE^® Cold Remedy Oral Spray is formulated with zinc gluconate, the same effective active ingredient found in the best-selling, clinically proven and #1 pharmacist recommended Cold-EEZE^® lozenges. The effective proprietary formula reduces the duration of the common cold.

Other key facts include:

• Each bottle contains at least 45 doses (90 sprays).
• The recommended two sprays per usage offer 13.3 mg of zinc gluconate, the same amount of cold remedy as in one Cold-EEZE^® lozenge.
• The new offering is available in a convenient, easy to carry spray bottle.
• Shortens your cold, works fast.
• #1 Pharmacist Recommended.
• Take at the first sign of a cold.

Learn More!