
Cold-EEZE® Cold Remedy lozenges have been clinically proven to shorten the duration of the common cold by almost half. The efficacy of our best selling lozenges is backed by double blind placebo controlled studies conducted at both the prestigious Cleveland Clinic and Dartmouth College.
Cold-EEZE® is a homeopathic cold remedy made with a unique zinc gluconate formula. Perhaps you’ve heard about zinc gluconate in the health section of your newspaper or seen it on lists of common cold tips on the Internet. Zinc is a micronutrient that’s essential to human health. In a well-formulated cold remedy, zinc gluconate facilitates the effective release of zinc ions which can shorten a cold.
Scientific theory* suggests that once a person has been exposed to a cold virus, the virus attaches to receptors in the upper respiratory system and replicates. It’s further believed that zinc ions released into the throat compete for these same receptors and thereby prevent the cold virus from reproducing. The virus dies off faster and the cold ends sooner.
Zinc gluconate is the active ingredient in Cold-EEZE®, the #1 pharmacist recommended zinc cold remedy and the best-selling zinc lozenge. Unlike some other zinc remedies, the Cold-EEZE® unique zinc gluconate formula does not contain additives that might interfere with the release of zinc ions. Cold-EEZE® zinc gluconate cold remedy is free of artificial colors or preservatives.
*Although the precise mechanism by which zinc ions interfere with the cold virus has not been scientifically established, the Cleveland Clinic study demonstrated that Cold-EEZE lozenges significantly reduced the duration of the common cold.
Prasad AS, Beck FWJ, Bao B, Snell D, Fitzgerald JT. Duration and severity of symptoms and level of plasma Interleukin-1 receptor antagonist, soluble tumor necrosis factor receptor, and adhesion molecules in patients with common cold treated with zinc acetate. Journal of Infectious Diseases 2008; 197:795-802.
Novick SG, Godfrey JC, Godfrey NJ, Wilder HR. How does zinc modify the common cold? Clinical observations and implications regarding mechanisms of action. Medical Hypotheses 1996; 46:295–302.
You don't have to take our word for it! Cold-EEZE® is backed by published, peer-reviewed clinical studies that show the powerful and safe effects of its unique formula.
Cold-EEZE lozenges are proven to shorten the duration of the common cold by the Cleveland Clinic (1996) and Dartmouth College (1992) studies. You can view and download these studies, and see a list of other relevant studies, below!
Geist, et al., 1987
Geist F, Bateman J, Hayden F. In vitro activity of zinc salts against human rhinoviruses.
Antimicrobial Agents and Chemotherapy 1987;31:622–4.
Novick, et al., 1996
Novick SG, Godfrey JC, Godfrey NJ, Wilder HR. How does zinc modify the common cold? Clinical observations and implications regarding mechanisms of action. Medical Hypotheses 1996;46:295–302.
Korant, et al., 1976
Korant BD, Butterworth BE. Inhibition by zinc of rhinovirus protein cleavage: interaction of zinc with capsid polypeptides. Journal of Virology 1976; 18: 298-306.
Prasad, et al., 2008
Prasad AS, Beck FWJ, Bao B, Snell D, Fitzgerald JT. Duration and severity of symptoms and level of plasma Interleukin-1 receptor antagonist, soluble tumor necrosis factor receptor, and adhesion molecules in patients with common cold treated with zinc acetate. Journal of Infectious Diseases 2008; 197:795-802.
Eby, 2004
Eby GA. Zinc lozenges: cold cure or candy? Solution chemistry determinations. Bioscience Reports 2004;24:23–39.
Singh, et al., 2011
Singh M, Das RR. Zinc for the common cold. Cochrane Database of Systematic Reviews 2011, Issue 2. Art. No.: CD001364. DOI: 10.1002/14651858.CD001364.pub3.
