About Cold-EEZE^®:
Using Zinc Gluconate For Colds

Cold-EEZE Cold Remedy lozenges have been clinically proven to shorten the duration of the common cold by nearly half. The efficacy of our best selling lozenges is backed by double blind placebo controlled studies conducted at both the prestigious Cleveland Clinic and Dartmouth College.

How Cold-EEZE Works

Cold-EEZE is a homeopathic cold remedy made with a unique zinc gluconate formula. Perhaps you’ve heard about zinc gluconate in the health section of your newspaper or seen it on lists of common cold tips on the internet. Zinc is a micronutrient that’s essential to human health. In a well-formulated cold remedy, zinc gluconate facilitates the effective release of zinc ions which shorten the common cold.

Scientific theory suggests that once a person has been exposed to a cold virus, the virus attaches to receptors in the upper respiratory system and replicates. It’s further believed that zinc ions released into the throat compete for these same receptors and thereby prevent the cold virus from reproducing. The virus dies off faster and the cold ends sooner.

Zinc gluconate is the active ingredient in Cold-EEZE, the #1 pharmacist recommended zinc cold remedy and the best-selling zinc lozenge. Unlike some other zinc remedies, the Cold-EEZE unique zinc gluconate formula does not contain additives that might interfere with the release of zinc ions. Cold-EEZE zinc gluconate cold remedy is free of artificial colors or preservatives.

Although the precise mechanism by which zinc ions interfere with the cold virus has not been scientifically established, the Cleveland Clinic Study demonstrated that Cold-EEZE lozenges significantly reduced the duration of the common cold.

Prasad AS, Beck FWJ, Bao B, Snell D, Fitzgerald JT. Duration and severity of symptoms and level of plasma Interleukin-1 receptor antagonist, soluble tumor necrosis factor receptor, and adhesion molecules in patients with common cold treated with zinc acetate. Journal of Infectious Diseases 2008; 197:795-802.

Novick SG, Godfrey JC, Godfrey NJ, Wilder HR. How does zinc modify the common cold? Clinical observations and implications regarding mechanisms of action. Medical Hypotheses 1996; 46:295–302.

For Best Results:

• Cold-EEZE treatment should begin within 24-48 hours of the start of a cold and be used daily until all symptoms resolve. The earlier, the better.
• Completely dissolve a Cold-EEZE lozenge in your mouth. Do not chew. Repeat every 2 to 4 hours as needed.
• The recommended daily dosage is 6 lozenges per day, which means an 18 count bag/box is a 3-day supply of Cold-EEZE for adults.
• Children 12-17 can take 4 lozenges per day.
• Consult your healthcare professional before giving Cold-EEZE to children under 12 years of age.
• Cold-EEZE is safe to take with most other medications including other symptom relievers.
• Avoid stomach upset — do not take Cold-EEZE lozenges on an empty stomach.
• Avoid citrus fruits and juices, as well as other products containing citric acid, 30 minutes before and after taking Cold-EEZE lozenges, as they may diminish product effectiveness.
• Zinc may interfere with the absorption of minocycline, doxycycline, tetracycline as well as Coumadin. If you’re taking one of these medicines, consult with your physician prior to using Cold-EEZE.
• Clinical studies demonstrated that results will vary but that on average, Cold-EEZE will shorten your cold by nearly half. As a consumer, if you are not satisfied with the results from taking Cold-EEZE, please contact us to receive a full refund of your purchase price.

Learn more about the clinical research behind Cold-EEZE and how it shortens your cold to help you get well sooner!

Get well sooner ... with Cold‐EEZE®

You don't have to take our word for it! Cold-EEZE has peer reviewed and published clinical studies that show the powerful and safe effects of its proprietary formula.

	An Open-Label Single-Center, Phase IV Clinical Study of the Effectiveness of Zinc Gluconate Glycine Lozenges (Cold-Eeze) in Reducing the Duration and Symptoms of the Common Cold in School-Aged Subjects
	Zinc Gluconate and the Common Cold: a Controlled Clinical Study
	Zinc Gluconate Lozenges for Treating the Common Cold
	Effectiveness of Zinc Gluconate Glycine Lozenges (Cold-Eeze) Against the Common Cold in School-Aged Subjects: A Retrospective Chart Review

List of relevant scientific studies related to zinc and common colds:

Geist 1987
Geist F, Bateman J, Hayden F. In vitro activity of zinc salts against human rhinoviruses.

Antimicrobial Agents and Chemotherapy 1987;31:622–4.

Novick 1996
Novick SG, Godfrey JC, Godfrey NJ, Wilder HR. How does zinc modify the common cold? Clinical observations and implications regarding mechanisms of action.

Medical Hypotheses 1996;46:295–302.

Korant 1976
Korant BD, Butterworth BE. Inhibition by zinc of rhinovirus protein cleavage: interaction of zinc with capsid polypeptides.

Journal of Virology 1976;18:298–306.

Prasa 2008
Prasad AS, Beck FWJ, Bao B, Snell D, Fitzgerald JT. Duration and severity of symptoms and level of plasma Interleukin-1 receptor antagonist, soluble tumor necrosis factor receptor, and adhesion molecules in patients with common cold treated with zinc acetate.

J Infect Dis 2008; 197:795-802.

Eby 2004
Eby GA. Zinc lozenges: cold cure or candy? Solution chemistry determinations.

Bioscience Reports 2004;24:23–39.

Singh 2011
Singh M, Das RR. Zinc for the common cold. Cochrane Database of

Systematic Reviews 2011, Issue 2. Art. No.: CD001364.
DOI: 10.1002/14651858.CD001364.pub3.

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Two Sprays & Go!

Two Sprays & Go!

The new Cold-EEZE^® Cold Remedy Oral Spray is formulated with zinc gluconate, the same effective active ingredient found in the best-selling, clinically proven and #1 pharmacist recommended Cold-EEZE^® lozenges. The effective proprietary formula reduces the duration of the common cold.

Other key facts include:

• Each bottle contains 90 sprays, that’s 45 doses of Cold-EEZE!  Not only is our new Oral Spray convenient, it’s a great value too!
• The recommended two sprays per usage offer 13.3 mg of zinc gluconate, the same amount of cold remedy as in one Cold-EEZE^® lozenge.
• The new offering is available in a convenient, easy to carry spray bottle.
• Shortens your cold, works fast.
• #1 Pharmacist Recommended.
• Take at the first sign of a cold.

Learn More!