Your Health Is Our Number One Concern
General Safety Overview
Safety is a major concern of most people especially when health is at stake. That is why Cold-EEZE® has made it a priority to ensure the safety of the product.
Cold-EEZE is safe and effective for all adult patients. There are no significant safety risks or adverse effects associated with Cold-EEZE lozenges, when taken as directed.
- Dissolving lozenges, tablets or chewing a piece of gum on a full stomach can remedy most cases of stomach upset.
- Cold-EEZE may alter taste buds. This is normal and temporary.
- Limited drug interaction: When taken at the same time, zinc has been reported to make doxycycline, minocycline, or tetracycline less effective. Take zinc two hours after ingesting doxycycline, minocycline, or tetracycline.1
Warnings
Cold-EEZE lozenges are formulated to relieve cold symptoms, and may be insufficient treatment for influenza. If symptoms worsen, or persist beyond 7 days, consult a physician. If pregnant or breast-feeding, ask a health professional before using.
Attention
Cold-EEZE Nasal Spray Users. Please be advised that any Cold-EEZE nasal spray product that you have in your possession or that you might purchase from a retail establishment is currently out of date and should be destroyed immediately.
Dosage
- Zinc can help to promote the strength of the immune system, and is required for the development and activation of T-lymphocytes that help to fight infection.
- Zinc gluconate glycine (ZIGG™), the active ingredient in Cold-EEZE provides 13.3 mg of ionic zinc per lozenge, and 4.3 mg per sugar-free tablet. When taken as directed (up to 6 lozenges; 16 sugar-free tablets per day) there are no significant risks of excessive dosage with Cold-EEZE.
- Although the Recommended Dietary Allowance for zinc is 11 mg for adult men and 8 mg for adult women, much higher doses are typically used for specific complaints.
- The National Institutes of Health have set Upper Limits (ULs) of zinc intake ranging from 4 mg/day to 34 mg/day for children between birth and 18 years of age, and 40 mg/day for adults. However, ULs do not apply to individuals who are receiving zinc for medical treatment.
- The maximum daily intake of zinc (from all sources) should not exceed 150 mg.1
- In the event of overdose, inordinate amounts of daily zinc intake (over 300 mg/day over several weeks) have been associated with nausea, vomiting, abdominal cramps, diarrhea, reduced copper status, reduced HDL-cholesterol levels and impaired immunological response.2
- When taken as directed, the typical course of therapy for Cold-EEZE results in an intake of 80 mg/day of ionic zinc for 3 to 7 days. When taking into account an average typical dietary zinc intake of 11 mg/day, the total daily intake is well within the limits of safety.
References
- Wholehealthmd.com. Supplements. Zinc-Drug Interactions. Available at: http://www.wholehealthmd.com. Accessed 09/16/08.
- Chandra RK. Excessive Intake of Zinc Impairs Immune Response. JAMA. 1984;252(11):1445.