Cold-EEZE® vs. Zicam Rapid Melts®

COLD-EEZE has clinical studies demonstrating its effectiveness. Zicam Rapid Melts and Zicam Chewables® do not.

COLD-EEZE dissolves more slowly releasing zinc ions evenly for up to 10 minutes.

It's clear why COLD-EEZE is the #1 Pharmacist Recommended Zinc Remedy.


Zinc Ion availability from 1 minute after dissolving (lozenge or melt) to 45 minutes after dissolving (lozenge or melt).

Degradation of Zinc comparing Cold-EEZE and Zicam Rapid Melts

Cold-EEZE lasts longer between doses offering extended dwell time of zinc ions. A Bio-availability study was conducted showing the change in the actual amount of available zinc ions (Zn2+) from 1 minute to 45 min was statistically less for Cold-EEZE than Zicam® Oral Melts, indicating that the Zicam Oral Melt degrades more rapidly than the Cold-EEZE lozenge after 45 minutes. (p < .0003) n=301

1. Bio-availability Study on Zinc Ion ( Zn2+) Clinical Research Labs, 2008. Report on file The Quigley Corporation.

Zicam® and Zicam Rapid Melts® are registered trademarks of Matrixx Initiatives Inc.