How the Cold-EEZE® Cold Shortening formulation works

Zinc gluconate is the active ingredient in Cold-EEZE®, the #1 pharmacist recommended zinc cold remedy** and the best-selling zinc lozenge**. Unlike some other zinc remedies, the Cold-EEZE® unique zinc gluconate lozenge formula does not contain additives that might interfere with the release of zinc ions. Cold-EEZE® zinc gluconate lozenge cold remedy is free of artificial colors or preservatives.

In addition to our cold shortening products made with zinc, we offer a variety of other Cold-EEZE products specially designed to relieve the symptoms associated with the common cold, flu or seasonal allergies.

**Based on the 2015 OTC Guide

Proven to Work

You don’t have to take our word for it! Cold-EEZE® is backed by published, peer-reviewed clinical studies that show the powerful and safe effects of our unique cold-shortening formula.

Clinical Studies

Cold-EEZE® lozenges have been clinically proven to shorten the duration of the common cold by almost half. The efficacy of the formula of our best-selling lozenges is backed by double blind, placebo-controlled studies conducted at both Cleveland Clinic and Dartmouth College. You can view and download these studies and see a list of other relevant studies below.


Cleveland Clinic Study (1996)


Dartmouth College Study (1992)


Additional Studies

Quality Assurance

Our goal is to help you feel better faster by developing high quality health care solutions that help you get back in the swing of things. We want you to be a satisfied Cold-EEZE® Fan!

We formulate Cold-EEZE® with high quality ingredients to provide you with great products, great solutions, and results! Cold-EEZE® products are manufactured in the United States in FDA registered facilities which follow Best Manufacturing Practices and maintain robust Quality Assurance Programs to ensure the safety, reliability, and precision of all our products. Every manufacturing run of Lozenges, QuickMelts®, Tablets, Capsules and Sprays are individually lot controlled and are tested and approved prior to leaving our facility.

All of us at Cold-EEZE® thank you for using our products. If you have questions or comments, you’re welcome to reach out to us at any time!

Doctor Recommended

I recommend Cold-EEZE to my patients at the very first sign of a cold. It’s terrific at shortening the duration of a cold, so you feel better faster.

Keri Peterson, MD

Dr. Keri Peterson obtained her bachelor degree from Cornell University and received her medical degree from Mount Sinai School of Medicine. She completed post-graduate training in Internal Medicine at Mount Sinai Medical Center in New York City and is board certified in Internal Medicine. Dr. Peterson has been in private practice with a prominent medical group on the Upper East Side of Manhattan since 1999.

Customer Approved

I tried Cold-EEZE last week after I felt a full-fledged bomb of a cold coming on. Man, oh man, it did the job!!! Thank you, thank you.

Joe R. | In good health, here in Buffalo, N.Y.

See More

Although the precise mechanism by which zinc ions interfere with the cold virus has not been scientifically established, the Cleveland Clinic study demonstrated that Cold-EEZE® lozenges significantly reduced the duration of the common cold.